By Eylül GÜNExploring tissue origins and age characteristics in endometriosis
By Eylül GÜN
Despite its widespread occurrence, the precise factors leading to endometriosis and the nature of its symptoms remain uncertain. To better understand the disease and improve treatment, Leap et al. from the US and Austria explored the use of DNA methylation…
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By Nasuhi Engin AydinSeparation of epithelia and stroma components in endometriosis lesions yields remarkable molecular points - Ie-Ming Shih, MD, Ph.D.
By Nasuhi Engin Aydin
The pathologies of adenomyosis and endometriosis are unique among non-malignant gynecological diseases and provide fertile research topics. Ectopic endometrial tissues may have distinct molecular changes distinct from eutopic endometria despite having similar morphology. In this regard, there are intriguing suggestions as…
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By Ellen TumimbangHormone Control Related Genes in Women With Endometriosis
By Ellen Tumimbang
Endometriosis is an estrogen-dependent disease. The development of endometriosis is stimulated by the specific ability to receive the estrogen that is needed for growth and differentiation of endometrial cells and has numerous biological functions in eutopic and ectopic endometrium. Estrogen…
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By Dr. Youngran ParkMachine Learning Classifiers for Endometriosis
By Dr. Youngran Park
Endometriosis is a complicated gynecological disorder that affects about 176 million women worldwide. It significantly impairs mental and physical quality of life in patients but the etiology is poorly understood. Endometriosis also causes a large economic burden due to loss…
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Epigenetic link between endometriosis and cancer
By Nasuhi Engin Aydin
Although endometriosis is considered a benign condition the cellular, histologic, and molecular data strongly demonstrate that endometriosis has neoplastic characteristics. There is strong evidence that endometriosis shares striking features with malignancy like normal tissue dissemination, invasion, and organ damage, as well as new vessel formation (neoangiogenesis). In…
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Epigenetic regulation of the pathological process in endometriosis.
By Dr. Youngran Park
Epigenetic mechanisms have been recognized as important players in the development of a broad range of human diseases including endometriosis. A growing body of evidence shows that the remodeling of retrograde endometrial tissues to the ectopic endometriotic lesions involves multiple epigenetic…
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